DEVELOPMENT OF TRIPTOLIDE SELF-MICROEMULSIFYING DRUG DELIVERY SYSTEM AND ITS ANTI-TUMOR EFFECT ON GASTRIC CANCER XENOGRAFTS

Development of Triptolide Self-Microemulsifying Drug Delivery System and Its Anti-tumor Effect on Gastric Cancer Xenografts

Purpose: To develop a triptolide (TP) self-microemulsifying drug delivery system and to investigate its anti-tumor effect on human gastric cancer line MGC80-3 xenografts in nude mice.Methods: The medium chain triglyceride (MCT) was selected as oil phase; polyoxyethylene castor oil (EL) was selected as surfactant, and PEG-400 was selected as cosurfa

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Flotillins interact with PSGL-1 in neutrophils and, upon stimulation, rapidly organize into membrane domains subsequently accumulating in the uropod.

BackgroundNeutrophils polarize and migrate in response to chemokines.Different types of membrane microdomains (rafts) have been postulated to be present in rear and front of polarized leukocytes and air force medical technician badge disruption of rafts by cholesterol sequestration prevents leukocyte polarization.Reggie/flotillin-1 and -2 are two h

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The End of Design Theory: A Project

By the advent of the Bauhaus, the notion of design did engage in a two-track operation.Without dissociating itself from themes central to the formation of the architectural discipline, the concept of design, on the one hand, had to recode and at times delete thematic that had attained dulces mara candy flavors visibility in the context of labour an

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